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The use of CBD hachis remains an emotionally and politically charged problem. Although cannabis oil preparations have been used in medicine for millennia, concern about the dangers of abuse led to the prohibition of the medicinal use of marijuana in the 1930s.
Recently, marijuana and chemically related compounds have once again been considered of therapeutic value. A prominent compound found in marijuana or hashishes, CBD or cannabidiol, has been shown to treat numerous diseases. Researchers believe that in view of the very low toxicity and generally benign side effects of CBD, neglecting or denying the benefits of CBD and its clinical potential is simply unacceptable.
What is CBD Hash?
The Cbd it is one of more than 60 compounds found in cannabis and belong to a class of ingredients called cannabinoids. Until recently, THC (tetrahydrocannabinol) captured the greatest attention because it is the ingredient in cannabis that produces effects that alter the minds of users, but the Cbd It is also present in high concentrations, and the medical world is realizing that its list of medical benefits continues.
CBD is the non-psychoactive component of Cannabis sativa. According to a 2013 study published in the British Journal of Clinical Pharmacology, the benefits of CBD include acting on some experimental models as anti-inflammatory, anticonvulsant, antioxidant, antiemetic, anxiolytic and antipsychotic people, and so it's a potential drug for the treatment of neuroinflammation, epilepsy, oxidative injury, vomiting and nausea, anxiety and schizophrenia.
Research is starting to show that CBD is different from other well-studied cannabinoids. All cannabinoids act as ligands, which means they dock at the binding site of a protein and have the ability to modulate the behavior of a receptor. CB1 receptors are widely distributed, but are particularly abundant in areas of the brain, including those related to movement, coordination, pain and sensory perception, emotion, memory, cognition, functions autonomous and endocrine functions.
CB2 receptors are mainly found in the immune system, and appear to reduce inflammation and certain types of pain. Although all cannabinoids have similar structures, they show a wide range of actions in each of the different receptors.
However, scientists are discovering that CBD it has very little effect on CB1 and CB2 receptors, which probably explains why it has no mind-altering effects, unlike THC, which positively regulates the CB1 receptor. That's why most marijuana grown for recreational purposes is usually very low in CBD and high in THC.
Proven benefits of CBD
1. Relieves pain and inflammation
Among the common benefits of CBD, natural pain relief tops the list for many. Evidence suggests that cannabinoids may be helpful in modulating pain by inhibiting neuronal transmission in pain pathways. A 2012 study published in the Journal of Experimental Medicine found that CBD significantly suppressed chronic inflammatory and neuropathic pain in rodents without causing analgesic tolerance. Researchers suggest that CBD and other non-psychoactive components of marijuana may represent a new class of therapeutic agents for the treatment of chronic pain.
According to a 2007 meta-analysis conducted in Canada, the combination of CBD and THC oral spray was effective in treating neuropathic pain in multiple sclerosis, which can be debilitating for 50 to 70 percent of MS patients.
2. Has antipsychotic effects
Research shows that the benefits of CBD include the production of antipsychotic effects. It appears to have a pharmacological profile similar to that of atypical antipsychotic drugs as seen using behavioral and neurochemical techniques in animal studies. In addition, studies show that CBD prevents human experimental psychosis and is effective in open case reports and clinical trials in patients with schizophrenia, with a noticeable safety profile.
3. Reduces anxiety
Studies using animal models of anxiety and involving healthy volunteers clearly suggest an anxiolytic effect of CBD. Cannabidiol has been shown to reduce anxiety in patients with social anxiety disorder and researchers suggest that it may also be effective for panic disorder, obsessive-compulsive disorder, social anxiety disorder and social anxiety disorder post-traumatic stress.
A 2011 study aimed to compare the effects of a public speaking simulation test on healthy control patients and native treatment patients with social anxiety disorder. A total of 24 patients never treated with social anxiety disorder received CBD or placebo 1.5 hours before the test. Researchers found that CBD pretreatment significantly reduced anxiety, cognitive decline and discomfort in speech performance, and significantly decreased alertness in anticipation of your speech. The placebo group had increased anxiety, cognitive impairment and discomfort.
4. Helps fight cancer
Several scientific reports show that the benefits of CBD include antiproliferative, pro-apoptotic effects that inhibit the migration, adhesion and invasion of cancer cells. ( 9) A 2006 study published in the Journal of Pharmacology and Experimental Therapeuticsfirst discovered that CBD powerfully and selectively inhibited the growth of different cell lines of breast tumors and exhibited significantly less potency in non-cancerous cells.
In 2011, researchers added light on the cellular mechanism through which CBD induces cell death in breast cancer cells. They showed that CBD induced a cell death dependent on the concentration of both estrogen-positive receptor-negative breast cancer cells for the receptor and estrogen. They also found that effective concentrations of CBD in tumor cells have little effect on non-tumor breast cells.
CBD behaves like a non-toxic compound and studies show that doses of 700 milligrams per day for 6 weeks showed no manifest toxicity in humans, suggesting that it may be used for prolonged treatment. Research not only shows that the benefits of CBD include being effective in fighting breast cancer cells, data also suggest that it can be used to inhibit the invasion of lung and colon cancer, it also possesses anti-tumor properties in gliomas and has been used for the treatment of leukemia.
5. Relieves nausea
Cannabis has been used for centuries for the suppression of nausea and vomiting. Research has revealed that among more than 80 cannabinoid compounds found in marijuana, both intoxicating THC and non-intoxicating CBD help eliminate nausea and vomiting in animal studies. A 2012 study published in the British Journal of Pharmacology discovered that the benefits of CBD include possession of antiemetic and antiemetic effects when administered to rats. Researchers found that CBD acts in a dilassitic manner, meaning that at low doses it suppresses toxin-induced vomiting, but at high doses increases nausea or has no effect.
6. May treat seizures and other neurological disorders
A 2014 survey by stanford University researchers was presented to parents belonging to a Facebook group dedicated to sharing information on the use of cannabis enriched with cannabidiol to treat their children's seizures. Nineteen responses met the inclusion criteria for the study: a diagnosis of epilepsy and the current use of CBD-enriched cannabis. The average number of antiepileptic medications tested before using CBD cannabis was 12. Sixteen (84 percent) of the 19 parents reported a reduction in the frequency of attacks by their children while taking CBD cannabis. Of these, two reported total freedom for seizures, eight (42 percent) reported a more than 80 percent reduction in frequency of seizures, and six (32 percent) reported a seizure reduction of 25 to 60 percent. Other beneficial effects include increased alertness, better mood and better sleep; while side effects include drowsiness and fatigue.
Later in 2014, researchers reported preliminary results from a study involving children with treatment-resistant epilepsy in an expanded "compassionate use" program. Patients received a 98 percent purified oil-based CBD extract called Epidiolex, manufactured by GW Pharmaceuticals. After 3 months of treatment, 39 percent of all 23 patients had a reduction of more than 50 percent in seizures, with a 32 percent reduction in the median. These preliminary results support animal studies and survey reports indicating that CBD may be a promising treatment for treatment-resistant epilepsy and is generally well tolerated in doses of up to 25 milligrams per kilogram of body weight.
7. Decreases the incidence of diabetes
A 2006 study found that CBD treatment significantly reduced the incidence of diabetes in non-obese diabetic mice, from an incidence of 86 percent in untreated mice to a 30 percent incidence in CBD-treated mice. The benefits of CBD also showed a significant reduction in plasma levels of pro-inflammatory cytokines. A histological examination of pancreatic islets of CBD-treated mice revealed significantly reduced insulitis.
In 2013, the American Journal of Medicine published a study highlighting the impact of marijuana use on glucose, insulin and insulin resistance among American adults. The study included 4,657 adult men and women from the National Health Survey and Nutritional Examination from 2005 to 2010. Of the participants, 579 were current marijuana users and 1,975 previous users. Researchers found that current marijuana use was associated with 16 percent fewer fasting insulin levels. They also found significant associations between marijuana use and smaller waist circumferences, a factor related to the onset of diabetes symptoms.
8. Promotes cardiovascular health
A 2013 study published in the British Journal of Clinical Pharmacologyreports that CBD protects against vascular damage caused by a high glucose environment, inflammation or induction of type 2 diabetes in animal models; In addition, CBD was shown to reduce the vascular hyperpermeability (which causes the permeable intestine) associated with such environments.
CBD HASH vs. CBD THC HASH
The CBD and THC are the two main compounds in the marijuana plant and are the only two cannabinoids that have been well characterized to date. Many marijuana strains are known to have abundant THC levels and strains with a high CBD content are less common; However, with the medical community paying more attention to the therapeutic effects of CBD, that's starting to change.
Both compounds have important health benefits: THC has antispasmodic, analgesic, anti-temic, anti-inflammatory, appetite-stimulating and anti-emetic properties, and CBD has anti-inflammatory, anticonvulsant, antipsychotics, antioxidants, neuroprotective and immunomodulatory.
Clinical use of THC is often limited by its unwanted psychoactive side effects, and for this reason, interest in non-psychoactive phytocannabinoids, such as CBD, has increased substantially in recent years. In fact, CBD is used to reduce the intoxicating effects of THC, such as paranoia and memory impairment.
CBD hashish also seems to counteract the sleep-inducing effects of THC. This is what makes CBD hashism so attractive to the medical community, as the cause of psychoactive side effects has been an important barrier in the acceptance of medical marijuana. Although THC is known to cause anxiety and paranoia in some people, CBD acts to counteract those side effects. For this reason, the benefits of CBD hachis extend to be used in clinical trials in young children with epilepsy.
How to legally acquire CBD
Today it can acquire CBD products legally, in our shop you can find from CBD Hash to creams and oils and reaching flowers or CBD buds with a very low THC content.
CBD is one of more than 60 compounds found in cannabis that belong to a class of ingredients called cannabinoids; is the main non-psychoactive component of Cannabis sativa .
Research shows that the benefits of CBD include acting as an anti-inflammatory, anticonvulsant, antioxidant, antiemetic, anxiolytic and antipsychotic agent, and is therefore a potential drug for the treatment of neuroinflammation, oxidative injury, vomiting and nausea, anxiety and schizophrenia.
Many marijuana strains are known to have abundant THC levels and strains with a high CBD content are less common; However, with the medical community paying more attention to the therapeutic effects of CBD, that's starting to change. CBD is used to reduce the intoxicating effects of THC, such as paranoia and memory impairment.
In Spain it is legal to sell, hold and consume low THC products and high CBD content.